Psychiatry Residents Journal Club
Journal club will be held once a month during our regular PRO time: Wednesdays at 1-2PM in NC5.710. Lunch will be served. Our faculty advisor is Dr. Byerly.
Journal Club #16
Date: February 17, 2010
Presenter: Antigone
Attending: Thorton
Description:
Discussion of the work of the French Philosopher Psychoanalyst Jacques
Lacan, who thought some really complicated thoughts about the mind.
Download the article: Lacan.pdf
Journal Club #15
Date: January 20, 2009
Presenter: Marisa
Attending: Brenner
Description:
This article reviews studies of psychodynamic therapy to show us that
the that dynamic therapy works?
Download the article: internationalpsychoanalysis.net/2009/11/12/the-efficacy-of-psychodynamic-psychotherapy-by-jonathan-shedler/
Journal Club #14
Date: November 18, 2009
Presenter: Chris
Attending: Dr. Mohl
Description:
Discussion of a conceptualization of medical
students, their coping styles and outcomes of resilience vs.
burnout. Or you could think of it as a talk about medical
students and why
they're so bitter all the time... as if we don't already know!
Download the article:
- Dunn LB et al. A conceptual model of medical student well-being: promoting resilience and preventing burnout. Academic Psychiatry, Jan-Feb 2008, 32:1
Journal Club #11
Date: July 15, 2009
Presenter: Marisa
Attending: Dr. Byerly
Description:
TBA
Download the article:
Journal Club #10
Date: June 10, 2009
Presenter: Felicia
Attending: Dr. Tirado
Description:
Dr. Carlos Tirado will be our guest attending. We'll be discussing a
seminal paper in the substance abuse field - a JAMA article that lays
out the argument for defining addiction as a chronic disease.
Download the article:
Journal Club #9
Date: May 13, 2009
Presenter: Jason
Attending: Dr. Byerly
Description:
We will be discussing the cost-effectiveness/Quality of Life evaluation
from the CATIE trial. Dr. Byerly says: Not only does it have
interesting findings, but it discusses the major issues considered in
cost-effectiveness studies in general.
Download the article:
Journal Club #8
Date: April 15, 2009
Presenter: Phil
Attending: Dr. Bylery
Description:
Genetics in mental health: we'll be discussing the landmark studies
showing risk of depression with the serotonin transporter allele types.
Dr. Byerly will be our guest attending.
Download the articles:
- Jacobs et al. Stress-related negative affectivity and genetically altered serotonin transporter function: evidence of synergism in shaping risk of depression. Arch Gen Psychiatry. 2006 Sep;63(9):989-96.
- Kendler et al. The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication. Arch Gen Psychiatry. 2005 May;62(5):529-35.
Journal Club #7
Date: March 11, 2009
Presenter: Sunil
Attending: Dr. Bylery
Description:
Dr. Bylerly returns as our guest attending as
we discuss a landmark study that demonstrated that most of the
weight-gain associated effects was due to Histamine-1 blockade - by
using rodent models. It is a very undertstandable piece that also is of
great clinical relevance.
Download the article:
Journal Club #6
Date: Feburary 11, 2009
Presenter: Maneesh
Attending: Dr. Kozel
Description:
Dr. Andy Kozel will be our guest attending as we discuss one of his
recent papers on the neurobiology of deception. This session will be a
good introduction to reading neuroimaging papers, as this study has
elements of neuroimaging, clinical study, and developing a diagnostic
test design.
Download the article:
Journal Club #5
Date: January 14, 2009
Presenter: Tracy
Attending: Dr. Jarrett
Description:
An example of a well-designed psychotherapy trial. Dr. Robin Jarrett will be our guest attending.
Download the article:
Journal Club #4
Date: December 10, 2008
Presenters: Felicia and Marisa
Attending: Dr. Trivedi
Description:
Two STAR*D papers on medication augmentation in depression. Dr. Trivedi will be our guest attending.
Download the articles:
- Rush et al. Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression. NEJM 2006 Mar 23;354(12):1231-42.
- Trivedi et al. Medication augmentation after the failure of SSRIs for depression. NEJM 2006 Mar 23;354(12):1243-52.
Journal Club #3
November 12, 2008
Presenter: Michelle
Attending: Dr. Bylery
Description:
Primary publication of CATIE results (Lieberman, NEJM, 2005). We will
focus on design issues like patient population (unusually inclusive),
medication dosing (which was arguably unfair for some of the
treatments), and implications of the findings for clinical practice
(that older agents performed as good as newer agents at 100-1000 X's
less cost).
Download the article:
Download the articles
Journal Club #2
October 29, 2008
Presenters: Rachel
Attending: Dr. Bylery
Description:
We will be discussing article 1b as described above.
Journal Club #1
September 17, 2008
Presenters: Margaret and Rachel
Attending: Dr. Bylery
Description:
Two articles as a "set": First article: Classic Phase-III
(premarketing) study of clozapine vs. chlorpromazine that led to
clozapine's treatment-resistant FDA indication (Kane, Arch Gen
Psychiatry, 1988). This study is frequently lauded for its outstanding,
and "pure" efficacy design (quite different from CATIE). Second
article: a Janssen-funded study (makers of Risperdal) of clozapine vs.
risperidone (Bondolfi, Am J Psychiatry, 1988), which claims to compare
cloz vs. risp in treatment -resistant schizophrenia. The 2nd article is
a great example of how study design can be grossly manipulated to get
the biased results a drug company might want .
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