Opiate equavalencies

Drug IV (mg) PO (mg) frequency (hrs)
morphine 1 3 3-4
dilaudid 0.2 0.6 12-24
fentanyl 10 mcg - 1
methadone - 1 8-12
hydrocodone - 3 3-4
oxycodone - 2 3-4

rule of thumb IV:PO = 1:3


Converting to Duragesic (fentanyl patch)

Determine IV morphine requirement in mg per 24 hours and select the corresponding mcg/hr fentalyl dose patch

IV morphine (mg/24h) duragesic (mcg/h)
8-22 25
23-37 50
38-52 75
63-67 100
68-82 125
83-97 150


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